Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2018 Aug 3;20:163. doi: 10.1186/s13075-018-1660-6

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

PMC Copyright notice

Fig. 3 — a 3D μCT images of the tibia subchondral bone medial compartment (sagittal view) of mice in all groups. Quantitative analysis of structural parameters of subchondral bone by μCT. b Bone mineral density (BMD) and c bone volume/total tissue volume (BV/TV), n = 10 per group. *p < 0.05, compared with the wild-type (WT) osteoarthritis (OA) mice at 4 weeks (4w). d Immunohistochemical analysis of Osterix-positive cells (brown, red arrow) in the tibial subchondral region. The result showed that GPR120 knockout (KO) mice significantly increased the numbers of Osterix-positive cells in subchondral bone compared with the WT mice 4 week after OA surgery. Scale bar = 50 μm. 6w 6 weeks, Con sham control