Table 1.
Baseline data for patients and s-IGF-I in each of the quintiles of changing s-IGF-I (ΔIGF-I-q1–5)
| Parameter | Unit | Value | ||
|---|---|---|---|---|
| n | 354 | |||
| Age at index ischemic stroke | Years (SD) | 55.4 (11) | ||
| Sex | Missing (N) | 229/125 | ||
| Male/female (fraction) | 0.65 | |||
| Diabetes | Yes (N/fraction) | 67 (0.19) | ||
| Missing (N) | 0 | |||
| Hypertension | Yes (N/fraction) | 188 (0.53) | ||
| Missing (N) | 0 | |||
| Current smoking | Yes (N/fraction) | 136 (0.38) | ||
| Missing (N) | 0 | |||
| LDL level (ng/nL) | Mean (SD) | 3.3 (1.0) | ||
| Missing (N) | 27 | |||
| P-glucose (acute) | Mean (SD) | 6.5 (2.64) | ||
| Missing (N) | 8 | |||
| P-glucose (3 m) | Mean (SD) | 6.03 (2.29) | ||
| Missing (N) | 8 | |||
| Stroke severity (NIHSS) | Mean (20, 80%) | 5.3 (0.7, 10.2) | ||
| Missing (N) | 0 | |||
| Stroke outcome (mRS) 3 m | Mean(SD) | 1.85 (1.06) | ||
| Missing (N) | 5 | |||
| Stroke outcome (mRS) 2 yr | mRS (SD) | 1.77 (1.32) | ||
| Missing (N) | 2 | |||
| Dead (3-24 m) | Yes (n/fraction) | 9 (0.025) | ||
| Missing (N) | 0 | |||
| s-IGF-I (acute) | ng/mL (SD) | 172.8 (62.9) | ||
| Missing (N) | 0 | |||
| s-IGF-I (3 m) | ng/mL (SD) | 152.7 (55.7) | ||
| Missing (N) | 0 | |||
| ΔIGF-I (ng/mL), all data | ng/mL (SD) | 20.2 (51.0) | ||
| Missing (N) | 0 | |||
| Quintile of ΔIGF-I: | ΔIGF-I (ng/mL) | s-IGF-I acute (ng/mL) | Change (%) | |
| ΔIGF-I-q1 (SD) | − 48.3 (48.0) | 146.5 (53.7) | incr. 33.0 | |
| (N) | 71 | 71 | 71 | |
| ΔIGF-I-q2 (SD) | 1.6 (5.8) | 145.4 (44.6) | decr. 1.10 | |
| (N) | 72 | 72 | 72 | |
| ΔIGF-I-q3 (SD) | 20.8 (5.7) | 152.5 (56.0) | decr 13.5 | |
| (N) | 71 | 71 | 71 | |
| ΔIGF-I-q4 (SD) | 42.5 (7.2) | 178.9 (45.9) | decr 23.6 | |
| (N) | 70 | 70 | 70 | |
| ΔIGF-I-q5 (SD) | 85.9 (28.0) | 240.5 (57.6) | decr 35.7 | |
| (N) | 70 | 70 | 70 | |
Absolute ΔIGF-I (ng/mL) represents a subtraction of acute s-IGF-I by 3-month s-IGF-I. A negative numerical value represents an increase from the acute to 3-month time point, and a positive numerical value represents a decrease. Modified Rankin scale (mRS), low density lipoprotein (LDL), National Institutes of Health Stroke Scale (NIHSS). An extended version of the table with a comparison to data presented in 2011 is found in Additional file 2: Table S1