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. Author manuscript; available in PMC: 2018 Aug 14.
Published in final edited form as: Methods Mol Biol. 2016;1419:27–39. doi: 10.1007/978-1-4939-3581-9_3

Fig. 1.

Fig. 1

Activity-based probes for caspases. (a) Schematic of the key features of an activity-based probe. (b) Mechanism of a cysteine protease binding to an ABP with an acyloxymethyl ketone warhead. (c) Structures of two fluorescent activity-based probes for caspases, AB50 and LE22. Figure adapted from Ref. 3