Figure 1.

TBSS analysis of FA and RD volumes revealed lower FA values (in red-yellow) and higher RD values (in yellow) in anxious MDD group when compared with the nonanxious group.

Notes: Results are overlaid on axial slices from the MNI standard brain at a permutation-based threshold of P<0.05 (FWE corrected). The background images are T1-weighted MNI template brains denoted with MNI coordinates. No regions of increased FA or decreased RD were found in the groups.

Abbreviations: FA, fractional anisotropy; FWE, family-wise error; MDD, major depressive disorder; MNI, Montreal Neurological Institute; RD, radial diffusivity; TBSS, tract-based spatial statistics.