Table 2.

Locations of significant (P<0.05, FWE corrected) group differences between anxious and nonanxious depressions in FA and RD

Anxious vs nonanxious	Cluster index	Cluster voxels	MNI coordinates of peak side voxel			Mean FA or RD (post hoc)		Cohen’s d	Side	Anatomical regions
			x	y	z	Anxious (n=39)	Nonanxious (n=45)
FA	3	3,457	−23	−31	34	0.58	0.65	1.35	Bilateral Left	Forceps minor Superior longitudinal fasciculus, Unicinate fasciculus
	2	578	31	−60	13	0.57	0.63	1.78	Bilateral Left	Forceps major Superior longitudinal fasciculus
	1	102	−33	−51	27	0.47	0.54	0.89	Left	Superior longitudinal fasciculus
RD	1	12,541	−29	−3	22	5.78	5.25	0.83	Bilateral Left	Forceps major, forceps minor Superior longitudinal fasciculus

Notes: Anxious: anxious depression group; nonanxious: nonanxious depression group. The units of RD was 10⁻⁴ mm²/s.

Abbreviations: FA, fractional anisotropy; FWE, family-wise error; MNI, Montreal Neurological Institute; RD, radical diffusivity.