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. 2018 Jul 30;2018:2124390. doi: 10.1155/2018/2124390

Table 2.

Plasma levels of examined parameters and CA 15-3 in patients with breast cancer and in control groups.

Groups tested CCL2 CCR2 CA 15-3
(pg/mL) (ng/mL) (U/mL)
Breast cancer (median, range)

Stage I 192.81 (36.68-438.58)b/f 1.34 (0.11-8.17)a/f 17.15 (6.20-50.30)a/b/f
Stage II 227.22 (1.45-1631.48)b/f 0.93 (0.05-6.16)a/b/f 17.60 (4.40-48.10)a/b/f
Stage III and IV 398.55 (99.12-592.30)a/b/c/d/f 0.92 (0.34-3.81)a/b/f 27.75 (8.90-250.00)a/b/c/d/f
Total group 228.34 (1.45-1631.48)a/b/f 0.96 (0.05-8.17)a/f 19.20 (4.40-250.00)a/b/f

Control groups (median, range)

Benign breast tumor 118.64 (37.37-489.88)e 1.82 (0.05-7.67)e 14.00 (5.20-20.70)
Healthy women 155.17 (70.58-440.06) 3.45 (0.84-22.60) 13.40 (6.30-28.40)
Total control group 130.64 (37.37-489.88) 2.30 (0.05-22.60) 13.60 (5.20-28.40)

Notes: astatistically significant when patients with BC compared with healthy women.bStatistically significant when patients with BC compared with benign breast tumor group. cStatistically significant when patients with BC stages III and IV compared with patients with BC stage I. dStatistically significant when patients with BC stages III and IV compared with patients with BC stage II. eStatistically significant when patients with benign breast tumor compared with healthy women. fStatistically significant when patients with BC compared with total control group.