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. 2018 Aug 10;11:4769–4780. doi: 10.2147/OTT.S165144

Figure 4.

Figure 4

Ectopic expression of MSX1 induced cell-cycle G1/S arrest and apoptosis, suppressed Notch signal pathway activity, and upregulated apoptotic markers in cervical cancer cells.

Notes: (A) Flow-cytometric analysis of MSX1 expression in HeLa cells showed an increased percentage of G1/S-phase cells compared with the control. Quantitative representation of the results is shown on the right. **P < 0.01. (B) Western blot analysis of Notch signal pathway components, CCND1, and apoptosis markers.

Abbreviation: CCND1, cyclin D1.