Table 1.
Correlations between SIRT6 expression and clinicopathologic factors in Chinese Han patients with non-small cell lung cancer
| Characteristic | (n) |
SIRT6 expression |
Statistical significance | |
|---|---|---|---|---|
| Negative | Positive | |||
| All patients | 86 | 64 (74.42) | 22 (25.58) | |
| Age | NS | |||
| ≤ mean | 31 | 26 (83.87) | 5 (16.13) | |
| > mean | 55 | 38 (69.09) | 17 (30.91) | |
| Sex | NS | |||
| Male | 50 | 35 (70.00) | 15 (30.00) | |
| Female | 36 | 29 (80.56) | 7 (19.44) | |
| Smoking status | NS | |||
| Current/former | 54 | 37 (68.52) | 17 (31.48) | |
| Never | 32 | 27 (84.38) | 5 (15.62) | |
| Histological type | NS | |||
| Adenocarcinoma | 49 | 33 (67.35) | 16 (32.65) | |
| Squamous cell carcinoma | 37 | 31 (83.78) | 6 (16.22) | |
| Degree of differentiation | P = 0.033 | |||
| Well | 38 | 24 (63.16) | 14 (36.84) | |
| Moderate/poor | 48 | 40 (83.33) | 8 (16.67) | |
| Invasion of the visceral pleura | NS | |||
| No | 46 | 32 (69.57) | 14 (30.43) | |
| Yes | 40 | 32 (80.00) | 8 (20.00) | |
| TNM stage | P = 0.019 | |||
| I–II | 48 | 31 (64.58) | 17 (35.42) | |
| III–IV | 38 | 33 (86.84) | 5 (13.16) | |
| Lymph node metastasis | P = 0.024 | |||
| No | 37 | 23 (62.16) | 14 (37.84) | |
| Yes | 49 | 41 (83.67) | 8 (16.33) | |
Data presented as n or n (%) prevalence.
NS, no statistically significant between-group difference (P >0.05; Pearson’s χ2-test).