Figure 3. Lack of effects on SA1 responses by the antagonists to P2X receptors, ionotropic glutamate receptors, GABAA receptors and glycine receptors.
(A) Sample traces show slowly adapting type 1 (SA1) impulses elicited by a 38-µm whisker hair deflection in normal bath solution (control, upper panel) and in the presence of 100 μM PPADS (lower panel). (B) Summary data of the SA1 frequency at different time points during whisker hair deflection before (control, circles) and following the bath application of 100 μM PPADS (squares). (C-F) Similar to B except 100 μM BBG (C), 10 μM TNP-ATP (D), 10 μM CNQX plus 50 μM APV (E), or 20 μM BIC plus 50 μM STRY (F) was tested (n = 6 in each test). Data represent the mean ± SEM. No significant difference was found in each test, two-way ANOVA with Bonferroni post-hoc tests.