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. Author manuscript; available in PMC: 2018 Sep 5.
Published in final edited form as: Eur J Pharmacol. 2018 Jul 19;834:17–29. doi: 10.1016/j.ejphar.2018.07.018

Fig. 7.

Fig. 7.

Changes in inspiratory drive (tidal volume/inspiratory time, Vt/Ti) in conscious sham-operated rats (SHAM) and in rats with bilateral carotid sinus nerve transection (CSNX) following bolus injection of morphine (10 mg/kg. i.v.), and then exposure to hypoxic challenge (10% O2, 90% N2) for 20 min (top panel) or hypercapnic challenge (5% O2, 21% O2, 74% N2) for 20 min (middle panel) and then re-exposure to room-air. Maximal and total changes in tidal volume/inspiratory time (Vt/Ti) are shown in the bottom left and right panels, respectively. The data are presented as mean ± SEM. There were 6 rats in each group.