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. Author manuscript; available in PMC: 2018 Sep 5.
Published in final edited form as: Eur J Pharmacol. 2018 Jul 19;834:17–29. doi: 10.1016/j.ejphar.2018.07.018

Fig. 8.

Fig. 8.

Total changes in frequency of breathing (fR), tidal volume (Vt), minute ventilation (Ve), inspiratory time (TI), expiratory time (Te) and tidal volume/inspiratory time (Vt/ Ti) upon return to room-air following exposure to either hypoxic (10% O2, 90% N2) challenge (top panel) or hypercapnic (5% O2, 21% O2, 74% N2) challenge (bottom panel) in morphine-treated sham-operated rats (SHAM) and in morphine-treated rats with bilateral carotid sinus nerve transection (CSNX) * P < 0.05, significant change from pre-hypoxia levels. P< 0.05, CSNX versus SHAM.