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. 2018 Aug 14;13(8):e0202258. doi: 10.1371/journal.pone.0202258

Table 2. Age, sex, and age- and sex-adjusted clinical characteristics and thyroid function according to the PHQ9 score.

PHQ9 score P for difference
0–9 (n = 1655) 10–14 (n = 83) 15–27 (n = 25)
Age (years) 44.5 ± 0.4 40.9 ± 1.8 50.1 ± 2.9 0.016
Women (%) 50.9 68.7 72.0 0.001
College graduation (%) 36.8 ± 1.1 28.4 ± 5.1 22.3 ± 9.3 0.086
Household income (x10,000 KRW) 386.1 ± 6.8 297.6 ± 30.6 187.7 ± 55.7 <0.001
Alcohol intake ≥ 30 g/day (%) 13.2 ± 0.8 21.5 ± 3.6 28.0 ± 6.6 0.009
Current smoking (%) 23.6 ± 0.9 35.8 ± 4.2 28.5 ± 7.7 0.017
Diabetes (%) 9.8 ± 0.7 9.6 ± 3.2 25.8 ± 5.8 0.024
Hypertension (%) 21.7 ± 0.9 22.2 ± 4.2 31.7 ± 7.6 0.425
Self-reported coronary heart disease history (%) 1.1 ± 0.3 0.4 ± 1.1 0.0 ± 2.1 0.658
Self-reported cerebrovascular disease history (%) 0.8 ± 0.2 1.5 ± 1.1 15.7 ± 2.0 <0.001
Self-reported cancer history (%) 3.3 ± 0.4 4.1 ± 1.9 2.8 ± 3.5 0.895
fT4 (ng/dL) 1.25 ± 0.01 1.23 ± 0.02 1.22 ± 0.03 0.292
TSH (μIU/mL) 2.71 ± 0.05 2.49 ± 0.23 2.39 ± 0.42 0.519
Subclinical hypothyroidism (%) 3.3 ± 0.4 2.3 ± 2.0 7.4 ± 3.6 0.468
Subclinical hyperthyroidism (%) 2.3 ± 0.4 5.9 ± 1.8 12.1 ± 3.2 0.002
Subclinical hyperthyroidism (%)* 2.3 ± 0.4 6.1 ± 1.8 12.5 ± 3.3 0.001

Data are expressed as mean ± SE.

* Adjusted for age, sex, household income, Alcohol intake ≥ 30 g/day, current smoking, diabetes, and cerebrovascular disease history.