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. 2018 Aug 14;13(8):e0202368. doi: 10.1371/journal.pone.0202368

Table 1. Variables and experimental design levels for RSM.

Independent variables Coded symbols Levels
-1 0 1
Ethanol concentration (%) X1 40 60 80
Ultrasonic intensity (W/cm2) X2 1.6 3.3 5.0
Solid-liquid ratio (mg/mL) X3 20 25 30