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. Author manuscript; available in PMC: 2019 Aug 1.
Published in final edited form as: Fertil Steril. 2018 Aug;110(3):429–436. doi: 10.1016/j.fertnstert.2018.04.032

Table 2.

Proportion of Pregnancy Outcomes, and Obstetric and Delivery Complications among Fertile, Subfertile, and ART-Treated Women Stratified by Vaginal and Cesarean Delivery

All Vaginal P-vaginal Cesarean P-Cesarean P-All
Fertile Subfertile ART Fertile Subfertile ART
N 173,130 113,104 1,506 3,133 51,601 1,151 2,635 2,635
Pregnancy complications (%)
 Gestational Diabetes 5.3 4.2 7.6 6.8 <0.001 7.0 11.9 10.6 <0.001 <0.001
 Pregnancy Hypertension 11.6 9.4 11.3 11.6 <0.001 16.0 18.3 19.5 <0.001 <0.001
 Eclampsia 5.3 4.0 4.4 4.5 0.2 8.1 8.3 10.2 <0.001 <0.001
 Bleeding Problems 2.6 2.6 3.6 5.0 <0.001 2.3 3.5 5.0 <0.001 <0.001
 Placental abruption 1.2 0.8 0.9 1.5 <0.001 1.8 2.4 3.1 <0.001 <0.001
 Placenta previa 0.6 0.2 0.7 0.7 <0.001 1.1 2.6 6.4 <0.001 <0.001
 Vasa previa 0.0 0.0 0.0 0.0 0.9 0.1 0.2 0.6 <0.001 <0.001
 Placenta accreta 0.5 0.6 1.1 1.7 <0.001 0.2 0.2 0.7 <0.001 <0.001
 Placental complications (all) 2.2 1.6 2.6 3.9 <0.001 3.1 5.1 10.2 <0.001 <0.001
Delivery complications (%)
 Cephalopelvic disproportion 6.4 0.5 0.8 0.7 0.2 19.4 16.5 12.7 <0.001 <0.05
 Breech/malpresentation 11.1 5.4 5.1 4.8 0.3 24.7 23.6 24.4 0.8 <0.001
 Prolonged labor (>20 hrs) 2.9 3.0 4.2 2.6 <0.05 2.9 3.3 1.6 <0.001 <0.001
 Dysfunctional labor 17.1 7.2 7.9 7.0 0.5 38.5 35.1 30.1 <0.001 <0.001
 Dysfunctional and prolonged labor 17.4 7.5 8.4 7.3 0.4 38.8 35.4 30.2 <0.001 <0.001
 Febrile 6.3 5.9 6.4 7.4 <0.01 7.2 6.1 5.8 <0.01 0.1
 Fetal distress 24.3 17.8 18.2 19.1 0.2 38.5 36.1 30.8 <0.001 0.1
 Cord prolapse 0.3 0.1 0.1 0.2 0.7 0.7 1.0 1.1 <0.05 <0.001
 PROM 8.8 8.9 11.4 11.4 <0.001 8.3 8.0 8.3 0.9 <0.001
Length of gestation (weeks)
Mean (SD) 39.0(2.0) 39.0(1.9) 38.9(2.2) 38.8(2.2) <0.001 40.0(2.2) 38.6(2.4) 38.5(2.5) <0.001 <0.001
Gestational age (%)
 <28 weeks 0.5 0.4 0.8 0.6 <0.01 0.6 0.9 0.9 <0.1 <0.001
 28–33 weeks 1.5 1.0 1.4 1.8 <0.001 2.4 3.7 3.6 <0.001 <0.001
 34–36 weeks 5.3 5.1 5.8 7.2 <0.001 5.3 7.7 9.2 <0.001 <0.001
 ≥ 37 weeks 92.7 93.5 92.0 90.4 <0.001 91.7 87.8 86.3 <0.001 <0.001
Birthweight (grams)
Mean (SD) 3,299(582) 3,271(535) 3,257(585) 3,233(572) <0.001 3,367(660) 3,315(705) 3,282(685) <0.001 <0.001
Birthweight (%)
 Very low (<1,500g) 1.3 1.0 1.4 1.5 <0.01 1.9 2.6 2.5 <0.05 <0.001
 Low (1,500–2,399g) 5.6 5.1 6.1 6.4 <0.01 6.3 8.5 7.9 <0.001 <0.001
 Normal (≥2,500) 93.1 93.9 92.5 92.1 <0.001 91.8 88.9 89.6 <0.001 <0.001
Birthweight Z-score
 SGA 10.0 10.3 9.9 10.3 0.9 9.6 9.7 9.0 0.6 0.6
 LGA 7.4 5.3 6.6 5.3 0.9 11.9 11.4 11.2 0.5 <0.01