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. Author manuscript; available in PMC: 2018 Dec 4.
Published in final edited form as: Nat Struct Mol Biol. 2018 Jun 4;25(6):505–514. doi: 10.1038/s41594-018-0069-x

Figure 7: The effects of small molecule compounds and cardiomyopathy-causing mutations on the power produced by single molecules of β-cardiac myosin.

Figure 7:

a, Duty ratio, b, average force, and c, average power as a function of the load force F, calculated by Eqns. 2–5. All curves are calculated using values of detachment rate kinetics (k0, 𝛿), kcat, and kattach given in Table 1. Black: WT. Gray: DMSO. Blue: HCM or activators. Red: DCM or inhibitor.