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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: Anesthesiology. 2018 Sep;129(3):459–476. doi: 10.1097/ALN.0000000000002281

Table 1.

Potent GABAA Receptor Modulators Tested in Tadpoles and Zebrafish Larvae

Compound # Reference Name of Compound in Reference
1 Ramerstorfer et al.20 CGS-9598
2 Middendorp et al.8 Compound 11
3 Kopp et al.21 Valerenic Acid Derirative-10
4 Middendorp et al.8 Compound 20 (Structure not shown)
5 Maldifassi et al.9 Compound 31
6 Maldifassi et al.9 Compound 132
7* PubChem Compound Database PubChem CID: 43947938
8 Middendorp et al.8 Compound 67
9 Baur et al.22 4-O-methylhonokiol
10* PubChem Compound Database PubChem CID: 18593928
11* PubChem Compound Database PubChem CID: 3878620
*

Compounds 7, 10, and 11 have not been described in previous publications. Modulation of GABAA receptors by these compounds was confirmed by Constanza Maldifassi, PhD (Centro Interdisciplinario de Neurociencia de Universidad de Valparaíso, Valparaíso, Chile; personal communication). Compound information and available commercial vendors can be found in PubChem Compound Database (https://pubchem.ncbi.nlm.nih.gov/).