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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: Cell Immunol. 2018 May 14;331:38–48. doi: 10.1016/j.cellimm.2018.05.003

Table 3.

Incidence of IgG autoantibodies in the sera of Aire−/− and Aire+/+ HLA-DR2b and HLA-DR4 tg mice.

Genotype HLA-DR2b HLA-DR4
Gender Male Female Male Female
Aire+/+ mice 1/3 0/2 0/7 1/3
Aire−/− mice 2/10 2/9 2/10 2/8

IgG autoantibodies detected in the sera of Aire+/+ and Aire−/− HLA-DR2b or HLA-DR4 tg mice which was stained against a panel of organs (stomach, lung, liver, bowel, pancreas and kidney) from SCID mice, IgG binding was observed in the gastric tissue. Shown are the incidences of mice that have IgG auto-antibodies (n = 3–10).

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