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. Author manuscript; available in PMC: 2020 Jan 1.
Published in final edited form as: Shock. 2019 Jan;51(1):78–87. doi: 10.1097/SHK.0000000000001127

Table 1.

Histological findings of kidney tissue obtained after HS, treated with Cp40 or vehicle.

Parameter Ctrl HS + NaCl HS + CP40 Significance NaCl vs CP40
mean ± SEM mean ± SEM mean ± SEM
Glomeruli
Dilation 0.11 ± 0.06 0.73 ± 0.03* 0.65 ± 0.07* n.s.
Precipitation 0.11 ± 0.08 0.16 ± 0.10 0.05 ± 0.03 n.s.
Infiltration 0 ± 0 0 ± 0 0 ± 0 n.s.
Proximal Tubulus
Apoptosis 1.07 ± 0.07 1.40 ± 0.20 1.15 ± 0.05 n.s.
Dilation 1.53 ± 0.24 3.73 ± 0.37* 3.75 ± 0.38* n.s.
Distal Tubulus
Apoptosis 1.07 ± 0.07 1.13 ± 0.07 1.20 ± 0.12 n.s.
Dilation 1.13 ± 0.07 2.07 ± 0.18* 2.40 ± 0.29* n.s.
Neutrophil Infiltration
1.00 ± 0.00 1.07 ± 0.07 1.10 ± 0.10 n.s.
Brush Border Loss
1.20 ± 0.2 4.00 ± 0.33* 3.40 ± 1.35* n.s.
*

p<0.05 versus Ctrl (ANOVA, post-hoc SNK test)