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. Author manuscript; available in PMC: 2019 Dec 1.
Published in final edited form as: Dev Biol. 2018 Feb 14;444(Suppl 1):S79–S97. doi: 10.1016/j.ydbio.2018.02.003

Figure 1. RTK signaling pathways in isolation.

Figure 1

The ERK1/2 (A), p38 (B), JNK (C) ERK5 (D), and PI3K (E) pathways and their known or likely means of activation downstream of RTKs are shown at left. For simplicity only crucial adapter proteins are shown and specific effector proteins and crosstalk between pathways have been omitted. See the text for further clarification. To the right are demonstrated (bold) and suggested (regular) cellular downstream behaviors in NC.