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Time course of the development of ENaC currents with dietary Na restriction
Whole‐cell currents in principal cells of CCDs from rats on a low‐Na diet for (A) 3 days, (B) 5 days and (C) 7 days. Left: current traces in response to voltage jumps to –100 to +60 mV from a holding potential of 0 mV in the absence and presence of 10 μm amiloride in the bath solution. Right: I–V relationships in the absence and presence of amiloride, as well as the difference current (I Na).
