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. 2018 Jul 2;596(16):3553–3566. doi: 10.1113/JP275793

Figure 3. VEGF‐A inhibits IKCa and SKCa‐dependent EDH vasodilatation.

Figure 3

Arteries were perfused with either vehicle or 1 nm VEGF‐Afor 60 min. All experiments were performed in the presence of l‐NAME. Vehicle and VEGF‐A are from Fig. 2. A, vasodilatation to SLIGRL with the addition of TRAM‐34 (TR) (n = 5–13). B, vasodilatation with the addition of apamin (Ap) (n = 3–13). C, SLIGRL‐mediated vasodilatation in the presence of TRAM‐34 and apamin (n = 3–13). D, vasodilatation to 10 μm SLIGRL in the presence of IKCa and SKCa inhibitors. * < 0.05 compared to VEGF‐A. # < 0.05 compared to vehicle + TR.