Fig. 5. Intra-amygdala infusion of ZL006 impairs memory formation of auditory fear conditioning.

a Schematic of the behavioral protocol. Rats were given intra-BLA infusion of ACSF (n = 10) or 10 µM ZL006 (n = 9) immediately after fear conditioning and the retention of conditioned fear memory was tested 24 h later. b Both pre-assigned vehicle and ZL006 groups of animals showed normal cued fear acquisition (Trial: F_{2, 34} = 308.8, P < 0.0001). c Animals treated with ZL006 showed significantly reduced freezing responses in the fear expression test (Treatment: F_{1, 17} = 4.974, P < 0.05). *P < 0.05 relative to vehicle