Figure S5.

Functional Interaction of DLL1 and NOTCH2NL during Mouse Corticogenesis In Vivo, Related to Figure 7

(A and B) Original pictures of the result of co-immunoprecipitation of overexpressed NOTCH2NLB-full length-myc (N2NLFL-myc) and DLL1-GFP. The regions in the magenta rectangles are cropped for Figures 7A and 7B.

(C) Bin analysis of the regional distribution of electroporated cells in the mouse cortex 2 days after in utero electroporation at E13.5. The fraction of electroporated cells in the VZ and CP are highlighted in Figures 7J and 7K. Four conditions, Control mCherry alone, DLL1, DLL1 + NOTCH2NLB full length (DLL1+N2NL-FL), DLL1 + NOTCH2NL EGF repeats deletion (DLL1+ΔEGF), were tested.

Ventricular zone (VZ), the subventricular zone (SVZ), the intermediate zone (IZ), and the cortical plate (CP).

Data are represented as mean ± sem and p values by one-way ANOVA and bonferroni post hoc test.