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. 2018 Aug 15;7(8):61. doi: 10.1038/s41389-018-0074-2

Fig. 1. SOX2 expression is prognostic for clinical nasopharyngeal carcinoma.

Fig. 1

a Expression levels of SOX2 mRNA are significantly higher in nasopharyngeal carcinoma samples compared with normal nasopharyngeal tissues. Expression data of SOX2 mRNA were downloaded from the GSE53819 dataset. b Expression levels of SOX2 DNA copy number are significantly higher in head and neck samples compared with normal tissues from a TCGA data sets. c IHC staining of SOX2 in clinical nasopharyngeal tissues and peritumoral tisssues specimens. d Quantitative analysis of SOX2 protein expression in c. e Kaplan–Meier analysis of patients with high SOX2 protein-expressing nasopharyngeal carcinoma versus low SOX2 protein-expressing nasopharyngeal carcinoma. Statistical analysis was performed by log-rank test in a GraphPad Prism version 5.0 for Windows. Error bars ± SD. *P < 0.05. Data are representative from two independent experiments