Table 1. FAP expression profiling in various tumor types.
Cancer | Cell | Method | Reagents | Reference |
---|---|---|---|---|
Bone | Tumor | IHC | Mouse antibody (Santa Cruz Biotechnology, Inc.) | 98 |
Brain | Astrocyte, stem cell, stroma, macs/fibrocyte | ELISA, WB, IF, qRT-PCR | DuoSet ELISA kit (R&D systems), rat monoclonal D8 and D28 (Vitatex), mouse monoclonal F19 | 22 |
Breast | Fibroblast | IHC, IF, qRT-PCR | NR | 16 |
Breast | Stroma, tumor | IHC | Rabbit polyclonal antibody ab53066 (Abcam) | 34 |
Breast | Stroma, tumor | IHC | Polyclonal antibody (Abcam) | 36 |
Breast | Stroma, tumor | IHC | Polyclonal antibody (Abcam) | 35 |
Breast | NR | qRT-PCR | 99 | |
Colorectal | Stroma | IHC | Unspecified antibody (Abcam) | 47 |
Esophageal | NR | WB, RT-PCR | Rabbit polyclonal antibody N1N3 (GeneTex, Inc.) | 19 |
Esophageal | Stroma | ELISA, IHC, WB, qRT-PCR | DuoSet ELISA kit (R&D systems), sheep polyclonal antibody AF3715 (R&D) | 25 |
Esophageal | Stroma | IHC | Unspecified antibody (Abcam) | 54 |
Gastric | Stroma | IHC, IF | Unspecified antibody (Boster Biological Technology) | 48 |
Gastric | Mesothelia | IHC | Rabbit polyclonal antibody (Abcam) | 40 |
Liver | Stroma | IHC | Rabbit polyclonal antibody SAB2900181 (Sigma) | 59 |
Liver | Stroma | IHC | Rat monoclonal D8 (Vitatex) | 53 |
Lung | Tumor | IHC | Rabbit polyclonal antibody (Assay Biotech) | 31 |
Oral | Tumor | IHC, IF | Rabbit polyclonal antibody (LifeSpan BioSciences) | 51 |
Ovarian | Stroma, tumor | IHC | Rabbit polyclonal antibody LS-A8023 (LifeSpan BioSciences) | 52 |
Ovarian | Tumor, mesothelia | IHC, ISH | Rabbit polyclonal antibody ab53066 (Abcam) | 39 |
Pancreatic | Stroma, tumor | ELISA, IHC, IF | DuoSet ELISA kit (R&D systems), polyclonal antibody (LSBio), mouse monoclonal F19 | 20 |
Pancreatic | Stroma, tumor | IF | Mouse monoclonal F11-24 (Santa Cruz Biotechnology, Inc.) | 21 |
Pancreatic | Stroma, tumor | IHC | Rabbit polyclonal antibody ab53066 (Abcam) | 37 |
Pancreatic | Stroma, tumor | IHC, IF | Sheep polyclonal antibody AF3715 (R7D Systems), mouse monoclonal F19 | 38 |
Parathyroid | NR | RT-PCR, qRT-PCR | 15 | |
Renal | Stroma | IHC | Rabbit polyclonal antibody ab53066 (Abcam) | 45 |
Renal | Stroma | IHC | Rabbit polyclonal antibody ab53066 (Abcam) | 46 |
ELISA: enzyme linked immunosorbent assay. IF: immunofluorescence. IHC: immunohistochemistry. ISH: in situ hybridization. NR: not reported. (q)RT-PCR: (quantitative) reverse transcriptase polymerase chain reaction. WB: western blot.