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. 2018 Aug 14;24(30):3361–3373. doi: 10.3748/wjg.v24.i30.3361

Table 1.

Diagnostic criteria for non-alcoholic fatty liver disease according to the various guidelines

EASL NICE Asia-Pacific AISF AASLD
Required criteria Steatosis in > 5% of hepatocytes by either imaging or histology Excessive fat in the liver Hepatic steatosis by either imaging or histology Hepatic steatosis on either imaging or histology Evidence of hepatic steatosis either by imaging or histology
No other causes of steatosis No other causes of steatosis No other causes of steatosis No other causes of steatosis No other causes of steatosis
Insulin resistance No significant alcohol consumption No significant alcohol consumption No significant alcohol consumption No significant alcohol consumption
No coexisting chronic liver disease
Alcohol consumption threshold (men) 30 g/d 30 g/d 2 standard drink/d 30 g/d 21 standard drink/wk
140 g/wk 294 g/wk
Alcohol consumption threshold (women) 20 g/d 20 g/d 1 standard drink/d 20 g/d 14 standard drink/wk
70 g/wk 196 g/wk

EASL: European Association for the Study of the Liver; NICE: National Institute for Health and Care Excellence; AISF: Italian Association for the study of the Liver; AASLD: American Association for the Study of Liver Diseases; MRI: Magnetic resonance imaging.