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. 2018 Aug 8;9:917. doi: 10.3389/fphar.2018.00917

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Copyright © 2018 Huang, Shi, Guo, Feng, Feng, Liu, Li, Liang, Xiang, Lei, Ma and Fu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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BMS309403 suppressed the expression of ER stress related proteins. (A) The expression of GRP78, p-PERK, ATF4, CHOP, as measured by Western blotting analysis, in kidney tissue sections. The densitometry values of proteins were normalized with β-actin. ^∗∗∗∗P < 0.0001, ^∗∗∗P < 0.001, ^∗∗P < 0.01, ^∗P < 0.05. (B) Double immunofluorescence staining of ATF4 proteins in tubular epithelial cells. (C) Double immunofluorescence staining of CHOP proteins in tubular epithelial cells.