TABLE 2.
Case-crossover, Time-crossover, and Case-case Time-control Estimates of the Relationship Between Five Classes of Preventive Medications and Death
| Types of Prescriptions | Case-crossover OR (95% CI) | Time-controla OR (95% CI) | Case-case Time-controla OR (95% CI) |
|---|---|---|---|
| Lipid lowering | 0.39 (0.37–0.41) | 0.39 (0.38–0.41) | 0.99 (0.94–1.06) |
| Blood pressure regulating | 0.38 (0.37–0.39) | 0.40 (0.39–0.41) | 0.95 (0.92–0.98) |
| Glaucoma | 0.40 (0.38–0.42) | 0.39 (0.38–0.40) | 1.02 (0.96–1.08) |
| Glucose regulating | 0.39 (0.37–0.40) | 0.39 (0.38–0.41) | 0.99 (0.94–1.03) |
| Osteoporosis | 0.45 (0.42–0.48) | 0.39 (0.38–0.40) | 1.16 (1.08–1.23) |
OR, odds ratio; CI, confidence interval.
a
Average crossover estimate for reference medication among all cases meeting eligibility criteria.