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. 2018 Aug 14;19:439. doi: 10.1186/s13063-018-2781-6

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 2 — SPIRIT diagram for time schedule of enrolment, allocation, intervention and patient assessments. MMSE Mini-Mental State Examination, CAM Confusion Assessment Method, HADS Hospital Anxiety and Depression Scale, ADL Activities of Daily Living scale, IADL Instrumental Activities of Daily Living scale