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. 2018 Aug 14;18:402. doi: 10.1186/s12879-018-3315-2

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 5 — Sensitivity assess of F1/Y. pestis in various matrices. F1 protein/Y. pestis spiked into three simulated samples were assayed by Yersinia F1-strips. All the samples were diluted in the control reagents such as (a). human serum: 1:5 dilutions in PCB; Left: Y. p. test; Right: F1 test. (b). mouse blood: 1:10 dilutions in normal saline; Left: Y. p. test; Right: F1 test. (c). mouse BAL: 1:10 dilutions in normal saline. The human serum had the same detection limit (10³ CFU/ml and 4 ng/ml) as that in PCB; while for mouse blood and BAL, the detection sensitivity has decreases to some extent. (NC: normal saline control)