TABLE 2.

AACE/ACE ASCVD Risk Categories and LDL Cholesterol Treatment Goals

Risk Category	Risk Factors/10-Year Risk	Treatment Goals
		LDL Cholesterol (mg/dL)	Non-HDL Cholesterol (mg/dL)	Apo B (mg/dL)
Extreme risk	• Progressive ASCVD, including unstable angina in individuals after achieving an LDL cholesterol <70 mg/dL • Established clinical CVD in individuals with diabetes, stage 3 or 4 CKD, or HeFH • History of premature ASCVD (age <55 years male, <65 years female)	<55	<80	<70
Very high risk	• Established or recent hospitalization for ACS or coronary, carotid, or peripheral vascular disease; 10-year risk >20% • Diabetes or stage 3 or 4 CKD with one or more risk factor • HeFH	<70	<100	<80
High risk	• Two or more risk factors and 10-year risk 10–20% • Diabetes or stage 3 or 4 CKD with no other risk factors	<100	<130	<90
Moderate risk	Two or fewer risk factors and 10-year risk <10%	<100	<130	<90
Low risk	Zero risk factors	<130	<160	NR

NR, not recommended.