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. 2018 Aug 1;2018:6532320. doi: 10.1155/2018/6532320

Table 2.

Results of the multiple regression analyses: basic models.

  Predictor B SE t p R 2
Global health-related quality of life (n=242) Intercept 10.99 3.35 3.28 <0.001∗∗∗  
Gender: maleb −1.10 1.20 −0.92 0.361 0.00
Agea −0.00 0.07 −0.00 0.995 0.00
Disease duration 0.05 0.14 0.35 0.726 0.02
PANDAa −0.26 0.17 −1.58 0.116 0.01
BDI-II 0.93 0.09 10.44 <0.001∗∗∗ 0.28
NMSSa 0.09 0.02 4.04 <0.001∗∗∗ 0.16
UPDRS-IIIa 0.22 0.09 2.29 0.023∗ 0.05
H&Y 1.72 1.24 1.39 0.167 0.07
LEDDa 0.01 0.00 2.81 0.005∗∗ 0.05
    F(9,232) = 48.02, p < 0.001 Multiple R 2 0.65
          Adjusted R 2 0.64
Physical-functioning health-related quality of life (n=241) Intercept 16.99 4.95 3.43 <0.001∗∗∗ 0.01
Gender: maleb −4.67 1.79 −2.61 0.010∗∗ 0.01
Agea 0.03 0.10 0.26 0.798 0.01
Disease duration −0.04 0.22 −0.17 0.868 0.03
PANDAa −0.09 0.25 −0.38 0.706 0.01
BDI-II 0.81 0.13 6.23 <0.001∗∗∗ 0.15
NMSSa 0.13 0.03 3.90 <0.001∗∗∗ 0.13
UPDRS-IIIa 0.56 0.14 3.98 <0.001∗∗∗ 0.10
H&Y 3.02 1.84 1.64 0.101 0.10
LEDDa 0.01 0.00 3.19 0.002∗∗ 0.06
    F(9,231) = 37.80, p < 0.001 Multiple R 2 0.60
          Adjusted R 2 0.58
Cognition health-related quality of life (n=240) Intercept 0.99 4.63 0.21 0.831  
Gender: Maleb 6.97 1.66 4.21 <0.001∗∗∗ 0.03
Agea 0.14 0.09 1.52 0.131 0.01
Disease duration 0.16 0.20 0.82 0.416 0.01
PANDAa −0.55 0.23 −2.40 0.017∗ 0.02
BDI-II 1.16 0.13 9.07 <0.001∗∗∗ 0.26
NMSSa 0.09 0.03 2.86 0.005∗∗ 0.13
UPDRS-IIIa −0.13 0.13 −1.00 0.318 0.02
H&Y 2.80 1.70 1.65 0.100 0.04
LEDDa 0.00 0.00 0.75 0.453 0.02
    F(9,230) = 53.68, p < 0.001 Multiple R 2 0.55
          Adjusted R 2 0.53
Socioemotional health-related quality of life (n=241) Intercept 9.56 4.18 2.29 0.023∗  
Gender: Maleb −3.36 1.51 −2.23 0.027∗ 0.01
Agea −0.17 0.09 −1.94 0.053 0.01
Disease duration 0.12 0.17 0.66 0.510 0.01
PANDAa −0.25 0.21 −1.23 0.220 0.01
BDI-II 1.13 0.11 10.14 <0.001∗∗∗ 0.32
NMSSa 0.02 0.03 0.72 0.471 0.07
UPDRS-IIIa 0.20 0.12 1.73 0.085 0.02
H&Y −0.43 1.53 −0.28 0.779 0.02
LEDDa 0.00 0.00 0.83 0.407 0.01
    F(9,231) = 22.58, p < 0.001 Multiple R 2 0.47
          Adjusted R 2 0.45

Note. Parkinson's Disease Questionnaire 39 (PDQ-39) total score and the PDQ-39 component scores physical-functioning, cognition, and socioemotional HrQoL (as revealed by the principal component analysis) were used as dependent variables. BDI-II = Beck's Depression Inventory II; H&Y = Hoehn and Yahr stage; LEDD = levodopa equivalent daily dose; NMSS = Nonmotor Symptom Scale; PANDA = Parkinson Neuropsychometric Dementia Assessment; UPDRS-III = Unified Parkinson's Disease Rating Scale Part III. aVariable was mean-centered; bgender was dummy coded with female gender as the baseline group; ∗ p ≤ 0.05;  ∗∗ p ≤ 0.01;  ∗∗∗ p ≤ 0.001.