Table 2.
Transcripts containing GA- or C-rich motifs are more enriched in ESCRT-II immunoprecipitations compared with the total RIP-Seq library
Shown are the means of the distributions of RIP-Seq transcripts containing 30-nt stretches of the indicated nucleotides or dinucleotides (see “Experimental procedures” regarding allowance of mismatches) compared with the mean of the distribution of all ESCRT-II RIP-Seq transcripts. The p values were determined using a two-sided, unpaired t test comparing the distributions of the indicated RIP-Seq transcripts with the distribution of all ESCRT-II RIP-Seq transcripts.
| Transcripts | Mean enrichment value | p value |
|---|---|---|
| All RIP-Seq transcripts | 1.59 | |
| GA | 1.97 | 9.19 × 10−13 |
| AC | 1.78 | 0.06 |
| AU | 1.61 | 0.55 |
| CU | 1.6 | 0.88 |
| GU | 1.75 | 0.02 |
| CG | 1.67 | 0.2 |
| A | 1.65 | 0.24 |
| U | 1.68 | 0.21 |
| G | 1.6 | 0.88 |
| C | 1.83 | 7.76 × 10−5 |