Table 2.

MIC values for NDM variants under zinc-limited conditions (50 μm EDTA)

^a Antibiotic abbreviations used are as follows: Amp, ampicillin; Ceph, cephalothin; Cefotax, cefotaxime; Ceftaz, ceftazidime.

^b Variants are all expressed in the same strain, E. coli DH10B.

^c Control is an expression vector with no bla_NDM insert (pHSG298).

^d Reductions in individual MIC values (relative to NDM-1) are marked as follows: 2 dilution decrease in green, 2 dilution increase in yellow, 3 dilution increase in orange, 4 dilution increase in red, > 4 dilution increase in brown. Control is not included in color-coding.

^e Resistance for each variant is summarized and color-coded as described in the legend for Fig. 1.