Figure 1.

(a) Schematic showing the different seeding patterns used during this work. In Uniform 4 million cells were evenly seeded throughout scaffolds. In Asymmetrically seeded scaffolds, 3.6 million cells were seeded evenly throughout the scaffold and 400 000 cells seeded on the loaded surface of the scaffold. Surface Only scaffolds were not seeded with cells within the scaffold but only with 400 000 cells on the loaded surface. (b) Schematic showing the multi‐axial loading device used in the present study. The hip ball is lowered onto the white disc representing the scaffold. Compression is generated by raising and lowering the ball, and sliding friction is generated by rotating the ball, allowing for a sliding motion over the scaffold. [Colour figure can be viewed at http://wileyonlinelibrary.com]