Figure 1. Co-expression of PD-1 and PD-L1 in a Lung Cancer Patient.
(A) Gating strategy for analyzing PD-1 and PD-L1 expression in human patient samples where CD45+/CD3+ cells were classified as T cells, CD45+/CD3− cells as B cells, CD45+CD11c+ cells as DCs, CD45+CD11b+ cells as macrophages (Macs) and MDSCs, and CD45− cells within the tumor site as tumor cells.
(B) Expression of PD-1 and PD-L1 on the indicated cell types derived from PBMCs from a healthy human individual, a lung cancer patient, and the tumor site of the same patient.
See also Figures S1 and S2 and Table S1.
