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. 2018 May 25;218(6):966–978. doi: 10.1093/infdis/jiy243

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© The Author(s) 2018. Published by Oxford University Press for the Infectious Diseases Society of America. All rights reserved. For permissions, e-mail: journals.permissions@oup.com.

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Figure 2. — A, Heat map of a study participant with incident bacterial vaginosis (case K018). Time runs from left to right on the bottom of the heat map and is indicated by the days of study enrollment. Metadata at the top of the heat map includes sexual activity, by partner sex (female, pink; male, blue; and orange, unknown); menstruation status (menses = red); Nugent score (0–3, green; 4–6, yellow; 7–10, red; and 99, missing data); and community state type (CST1, light blue; CST2, dark blue; CST3, light green; CST4, dark green; and CST5, dark pink). The scale bar (at the bottom of the heat map) provides the fractional relative abundance of a given species, on a log scale. As the blue color bar gets brighter, the relative abundance of each microorganism increases. B, Heat map of a study participant with normal vaginal flora for the majority of the study (healthy woman K004). Time runs from left to right on the bottom of the heat map. Metadata at the top of the heat map include sexual activity, by partner sex (female, pink; male, blue; unknown, orange); menstruation status (menses, red); Nugent score (0–3, green; 4–6, yellow; and 7–10, red; missing data, 99); and community state type (CST1, light blue; CST2, dark blue; CST3, light green; CST4, dark green; and CST5, dark pink). The scale bar (at the bottom of the heat map) provides the fractional relative abundance of a given species, on a log scale. As the blue color bar gets brighter, the relative abundance of each microorganism increases.

Figure 2. — A, Heat map of a study participant with incident bacterial vaginosis (case K018). Time runs from left to right on the bottom of the heat map and is indicated by the days of study enrollment. Metadata at the top of the heat map includes sexual activity, by partner sex (female, pink; male, blue; and orange, unknown); menstruation status (menses = red); Nugent score (0–3, green; 4–6, yellow; 7–10, red; and 99, missing data); and community state type (CST1, light blue; CST2, dark blue; CST3, light green; CST4, dark green; and CST5, dark pink). The scale bar (at the bottom of the heat map) provides the fractional relative abundance of a given species, on a log scale. As the blue color bar gets brighter, the relative abundance of each microorganism increases. B, Heat map of a study participant with normal vaginal flora for the majority of the study (healthy woman K004). Time runs from left to right on the bottom of the heat map. Metadata at the top of the heat map include sexual activity, by partner sex (female, pink; male, blue; unknown, orange); menstruation status (menses, red); Nugent score (0–3, green; 4–6, yellow; and 7–10, red; missing data, 99); and community state type (CST1, light blue; CST2, dark blue; CST3, light green; CST4, dark green; and CST5, dark pink). The scale bar (at the bottom of the heat map) provides the fractional relative abundance of a given species, on a log scale. As the blue color bar gets brighter, the relative abundance of each microorganism increases.