Table 3.
Associations of Polytobacco Use Trajectory Groups With Substance Use and Mental Health Outcomes at 24-Month Follow-Up
| Outcomes (W5) | Tobacco use trajectory groups | |||||
|---|---|---|---|---|---|---|
| Chronic polyproduct users vs. Tobacco nonusers (ref) | Polyproduct users vs. Tobacco nonusers (ref) | Chronic polyproduct users vs. Polyproduct users (ref) | ||||
| Past month substance use | IRR | 95% CI | IRR | 95% CI | IRR | 95% CI |
| Alcohol use | 5.632** | 2.775, 8.489 | 3.524** | 2.888, 4.160 | 1.902** | 1.138, 2.667 |
| Marijuana use | 7.425** | 2.512, 12.338 | 5.344** | 2.256, 8.431 | 2.159** | 1.498,2.820 |
| Other illicit drug use | 9.286** | 5.424, 13.148 | 7.485** | 3.292, 11.677 | 2.366** | 1.598, 3.135 |
| Mental health outcomes | OR | 95% CI | OR | 95% CI | OR | 95% CI |
| Depression (CESD) | 1.469** | 1.146, 1.792 | 1.334** | 1.080, 1.588 | 1.101 | 0.714, 1.488 |
| Anxiety (RCADS-GAD) | 1.572** | 1.133, 2.011 | 1.236* | 1.043, 1.426 | 1.127 | 0.984, 1.277 |
| ADHD | 2.597** | 1.830, 3.364 | 1.394* | 1.053, 1.735 | 1.663** | 1.272, 2.054 |
N = 3393. IRR = Incidence Rate Ratio. OR = Odds Ratio. CI = Confidence Interval. Adjusted for parental education level, youth age, gender, ethnicity, other tobacco products use (eg, smokeless tobacco, cigars/cigarillos, dissolvable) in the past 6 months, and each outcome indicator at baseline. W5 = 24-month follow-up. Mental health outcomes were coded by 0 = Scores below the clinical cutoff and 1 = Scores above the clinical cutoff. Past month substance use outcomes were coded as a count variable indicating number of days of substance use in the past month. *p < 0.05, **p < 0.01.