Table 3.

Significant SNP and associated genes for D100 in the combined analysis and meta-analysis

SNP name	SSC	Location, bp	P (combined)–value1	P (meta-analysis)–value2	Associated gene3	Distance,4 bp	Gene function	Effect6(%)
MARC0055965	1	240,256,448	1.28 × 10−5	NA	7SK	−340,605	NA	0.070736
ALGA0018931	3	52,464,041	6.03 × 10 −6	7.91 × 10 −7	ENSSSCG000000 29325	+371,904	Translation	0.166871
MARC0101536	6	139,068,649	2.64 × 10−5	4.55 × 10 −7	ENSSSCG000000 23243	+217,561	DNA-templated and replication	0.052004
H3GA0053564	6	17,434,093	9.77 × 10 −7	2.00 × 10 −7	CCDC102A	Exons	NA	0.027472
WU_10.2_8_120377608	8	120,377,608	3.45 × 10 −6	9.10 × 10 −8	PITX2	+451,497	Skeletal muscle tissue development; animal organ morphogenesis	0.144018
ASGA0096290	8	120,840,701	2.24 × 10−5	3.73 × 10 −8	PLA2G12A	+244,286	Lipid and phospholipid catabolic process	0.094187
ALGA0051735	9	20,355,090	8.01 × 10−6	1.90 × 10−2	NA	NA	NA	0.113077
H3GA0032360	11	74,978,970	2.33 × 10−4	8.75 × 10 −9	DOCK9	−18,814	Small GTPase-mediated signal transduction	0.024394
WU_10.2_16_83745324	16	83,745,324	2.96 × 10−4	2.24 × 10 −9	ENSSSCG000000 17110	+233,640	Protein phosphorylation	0.022255

¹ P _(combined)–value = P-value from the combined analysis. The bold data in this column represent the significant SNP at genome-wide significant level; otherwise at the chromosome-wide significant level.

² P _{(meta-analysis)}–value = P-value from the meta-analysis. The bold data in this column represent the significant SNP at genome-wide significant level.

³ CCDC102A = coiled-coil domain containing 102A; PITX2 = paired-like homeodomain 2; PLA2G12A = phospholipase A2 group XIIA; DOCK9 = dedicator of cytokinesis 9. The associated genes in bold in this column represent these genes were associated with traits based on annotation.

⁴+/− = the location of SNP in downstream/upstream of the nearest gene.

⁵NA = not available.

⁶Effect = the proportion of additive genetic variance explained by the identified SNP.