Major adverse cardiovascular event (MACE)-free probability as a function of mental stress-induced left ventricular ejection fraction (LVEF) change score. Predicted survival curves showing probability of MACE-free survival as a function of mental stress-induced LVEF change of + 10%, +5%, 0%, −5%, and −10%, compared to at rest, adjusted for age, sex, resting LVEF, and heart failure severity. The number of patients at risk was 282 at year 0, 241 at year 1, 223 at year 2, 160 at year 3, 101 at year 4, and 42 at year 5. Since the survival plot represents predicted curves from the Cox model in which ejection fraction (EF) change is modeled as a continuous variable, the number at risk we provide is necessarily for the entire sample rather than strata. Note that the Schoenfeld residual test for proportional hazards for change in EF was not significant (=0.63), thus the modeled lines are proportional.