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. 2018 Aug 15;4(8):eaat2142. doi: 10.1126/sciadv.aat2142

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Copyright © 2018 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).

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Fig. 1 — (A) Relative distribution of methylated CpGs across intergenic (18%), genic (82%), intronic (42%), and exonic (40%) regions in the Aiptasia genome. (B) Normalized frequencies of methylated CpGs in different regions. Chi-square test shows significant differences between intergenic and genic regions and between exons and introns (****P < 0.0001). (C) Relative frequencies of methylated positions across a normalized gene model. All frequencies were normalized to the lengths of the corresponding regions.