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. 2018 Aug 15;13(8):e0200955. doi: 10.1371/journal.pone.0200955

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Fig 1 — A) Synaptases (pink balls) bind to ssDNA (represented by the green left-facing arrow at top) to form a nucleoprotein filament. B) The nucleoprotein filament samples ssDNA sequences between Okazaki fragments in replicating DNA. Synaptases promote annealing of the nucleoprotein filament to complementary ssDNA. C) The ssDNA oligo becomes joined to replicating DNA between Okazaki fragments. Completion of replication yields one nonrecombinant chromosome and one recombinant heteroduplex chromosome. D) A second round of replication and division yields one fully recombinant cell (green) and 3 nonrecombinant cells (yellow) from a cell bearing one initially recombinant target chromosome.