Figure 3. SthK channel pore and selectivity filter.
(A) SthK pore domain with selectivity filter carbonyls highlighted in red. Only two opposing subunits are shown to highlight the size of the water-filled pore, purple. (B) Pore radius as a function of the distance along the pore calculated with the program HOLE for all three SthK structures and compared to those for HCN1 and TAX-4. Lines colors and types as indicated in the figure. (C) Overlay of SthK (green) and HCN1 (grey) pore region. Side chains facing towards the pore axis are displayed as sticks. Selectivity filter of SthK-KcsA overlay (D), HCN1 (E) and TAX-4 (F) in stick representations.
