Table 2.
Full blood examination of the Tfrc+/R654H strain
| Mean ± SD | P | ||
|---|---|---|---|
| WT (n = 22) | Tfrc+/R654H (n = 18) | ||
| RBCs, × 1012/L | 9.57 ± 0.7 | 11.21 ± 1.2 | <.0001 |
| Hb, g/L | 14.2 ± 1.2 | 13.4 ± 1.4 | <.05 |
| HCT, % | 45.9 ± 2.5 | 41.3 ± 4.6 | <.0001 |
| MCV, fL | 47.6 ± 1.7 | 36.9 ± 2.5 | <.0001 |
| MCH, pg | 14.9 ± 0.4 | 12.0 ± 0.7 | <.0001 |
| MCHC, g/dL | 31.3 ± 1.3 | 32.6 ± 1.9 | n.s. |
| RDW, % | 18.7 ± 1.1 | 19.7 ± 1.0 | <.05 |
| WBCs, × 109/L | 8.69 ± 1.8 | 7.63 ± 2.5 | n.s. |
| Platelets, × 109/L | 972 ± 190 | 1057 ± 385 | n.s. |
| Reticulocytes, % | 5.2 ± 1.6 | 4.0 ± 2.0 | n.s. |
Blood parameters obtained from 7-week-old WT and heterozygous (Tfrc+/R654H) mice using automated blood analyzer (Hemavet). Two-tailed Student t test was used.
Hb, hemoglobin; HCT, hematocrit; MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentration; n.s., not significant; RDW, red-cell distribution width; SD, standard deviation; WBC, white blood cell.