Table 2.
Multivariable analysis for factors associated with overall mortality after diagnosis of subsequent solid cancer
| Factor | Autologous (N = 217) | Allogeneic (N = 496) | ||||
|---|---|---|---|---|---|---|
| No. | Hazard ratio (95% CI) | P | No. | Hazard ratio (95% CI) | P | |
| Patient sex | ||||||
| Male | 142 | 1.00 (reference) | ||||
| Female | 75 | 0.59 (0.36-0.97) | .039 | |||
| Year of diagnosis of solid cancer | ||||||
| 1993-1999 | 9 | 2.45 (1.14-5.26) | .022 | |||
| 2000-2004 | 31 | 0.79 (0.42-1.49) | .47 | |||
| 2005-2009 | 52 | 0.80 (0.46-1.39) | .44 | |||
| 2010-2015 | 125 | 1.00 (reference) | ||||
| Duration from transplantation to cancer diagnosis (per year) | 496 | 0.94 (0.91-0.98) | .005 | |||
| Cancer type | ||||||
| Oral cavity/pharynx | 109 | 1.00 (reference) | ||||
| Esophagus | 76 | 2.43 (1.52-3.90) | <.001 | |||
| Stomach | 28 | 1.06 (0.48-2.34) | .89 | |||
| Colon | 43 | 1.35 (0.74-2.45) | .32 | |||
| Liver | 6 | 3.01 (0.92-9.90) | .069 | |||
| Pancreas | 15 | 6.78 (3.29-14.0) | <.001 | |||
| Lung | 43 | 2.54 (1.45-4.46) | .001 | |||
| Bone/soft tissue | 22 | 1.82 (0.91-3.65) | .093 | |||
| Skin | 24 | 0.69 (0.27-1.78) | .44 | |||
| Breast | 24 | 0.14 (0.02-1.05) | .056 | |||
| Cervix uteri | 8 | 0.84 (0.20-3.55) | .82 | |||
| Corpus uteri | 9 | 0.43 (0.06-3.13) | .40 | |||
| Prostate | 10 | 0.69 (0.16-2.89) | .61 | |||
| Kidney | 5 | 0.92 (0.12-6.71) | .93 | |||
| Bladder | 12 | 0.63 (0.15-2.63) | .52 | |||
| Central nervous system | 14 | 4.12 (2.01-8.45) | <.001 | |||
| Thyroid | 22 | 0.12 (0.02-0.87) | .036 | |||
| Others | 26 | 2.21 (1.13-4.33) | .021 | |||