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. Author manuscript; available in PMC: 2018 Aug 15.
Published in final edited form as: J Pharm Sci. 2017 Nov 21;107(3):922–933. doi: 10.1016/j.xphs.2017.10.042

Figure 4: In vitro studies of chemo- radiotherapy.

Figure 4:

A) Release profile of fluorescence from chitosan hydrogels loaded with free FITC or BSA-FITC, and BSA-FITC encapsulated in alginate microparticles (mAlg) and incorporated in chitosan hydrogels for 42 days (n=3). B) Percent of radioactive leakage of 131I-HSA out of 75mg/ml alginate microparticles loaded inside ct hydrogels for 42 days (n=3). Note insert that shows minimal (less than 1%) radioactive leakage. C) Drug release profile from chitosan hydrogels loaded with temozolomide (TMZ) for 48 hours (n=3). D) The effect of TMZ concentrations (0 – 100 μM) of free-drug or TMZ-hydrogels for three days on the survival of D54 cells analyzed by MTT (n=3).