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. Author manuscript; available in PMC: 2018 Dec 18.
Published in final edited form as: Nat Med. 2018 Jun 18;24(8):1257–1267. doi: 10.1038/s41591-018-0058-y

Figure 5. LFO activity increased with Direct Current Stimulation (DCS) in acute (anesthetized) recording sessions.

Figure 5

a. Recording and stimulation arrangement in acute experiments. b. LFP power before and during DCS shown in one session. Grey shaded area shows 1.5-4Hz frequency range. Thick lines in blue and red show mean and shaded areas show SEM. Inset shows 1.5-4Hz power in pre-DCS and during-DCS in all 11 sessions from 10 rats (mean and SEM shown in bar plots with individual values, two-tailed paired t-test, t(10) = -2.493, *p = 0.032). c. Spiking activity of the same neurons from a session before and during stimulation, showing increased coherent spiking during DCS. d. Mean SFC (dark red/blue line - conventions as previous) of 50 neurons from 10 rats. Shaded area represents SEM. 1.5-4Hz SFC (grey shaded area) increased with DCS (one-tailed paired t-test, t(49) = -1.727, *p = 0.045).