Fig. 10.

Hydroxylations of lysyl residues. (A) Collagen polypeptide lysyl 111 hydroxylation mediated by LH1/LH2/LH3.¹⁹⁶ In contrast to LH1 and LH2, LH3 can further modify hydroxylysyl 112 to galactosyl hydroxylysyl 113 and glucosylgalactosyl hydroxylysyl 114.¹⁸⁸ (B) Reactions catalyzed by JMJD6/JMJD4 on lysyl residue in post-translational modifications of proteins.^{193, 194}