Table 4.
Core laboratory antibody data for samples obtained at the time of transplantation.
| Characteristics, n (%) | Sensitized (n = 129) |
|---|---|
| Antibody Class | |
| Class I Only | 56 (43.4) |
| Class II Only | 24 (18.6) |
| Class I and II | 49 (38.0) |
| Class I (with or without Class II) | 105 (81.4) |
| Class II (with or without Class I) | 73 (56.6) |
| MICA Antibody | |
| Negative | 110 (85.3) |
| Positive | 19 (14.7) |
| Presence of at Least 1 Antibody in MFI Threshold | |
| 1000–3999 | 122 (94.6) |
| 4000–7999 | 54 (41.9) |
| >8000 | 42 (32.6) |
| Maximum MFI Threshold | |
| 1000–3999 | 64 (49.6) |
| 4000–7999 | 23 (17.8) |
| >8000 | 42 (32.6) |
| Maximum MFI Threshold for Class I Antibodies | |
| 1000–3999 | 56 (43.4) |
| 4000–7999 | 20 (15.5) |
| >8000 | 29 (22.5) |
| No Class I Antibodies | 24 (18.6) |
| Maximum MFI Threshold for Class II Antibodies | |
| 1000–3999 | 42 (32.6) |
| 4000–7999 | 8 (6.2) |
| >8000 | 23 (17.8) |
| No Class II Antibodies | 56 (43.4) |
| Calculated PRA per UNOS Calculator, mean ± standard deviation | |
| >1000 | 41.3 ± 35.76 |
| >4000 | 23.8 ± 35.02 |
| >8000 | 15.4 ± 30.38 |
MICA, major histocompatibility complex class I-related chain A; MFI, median fluorescence intensity; PRA, panel reactive antibody; UNOS, United Network for Organ Sharing