Table 2.

Cox-proportional hazard regression models for the all-cause death by the proportion of days covered (PDC) with stratification by sex.

	Proportion of days covered (PDC)									P for trend
	≥0.80	0.60–0.79		0.40–0.59		0.20–0.39		<0.20
		Hazard ratio	95% CI	Hazard ratio	95% CI	Hazard ratio	95% CI	Hazard ratio	95% CI
Total No. of participants	N = 22,261	N = 11,459		N = 10,279		N = 10,393		N = 10,675
Total person-years	210,743.9	107,681.9		96,106.9		96,505.9		98,115.7
All [No. of death]	N = 2,728	N = 1,513		N = 1,484		N = 1,617		N = 1,819
Model 1	Reference	1.20	1.13–1.28	1.29	1.21–1.37	1.37	1.29–1.46	1.47	1.39–1.57	<0.001
Model 2		1.19	1.12–1.27	1.26	1.18–1.34	1.34	1.26–1.43	1.45	1.36–1.54	<0.001
Men [No. of death]	N = 1,776	N = 1,009		N = 998		N = 1,050		N = 1,0.170
Model 1	Reference	1.24	1.14–1.33	1.33	1.23–1.44	1.39	1.29–1.50	1.50	1.39–1.62	<0.001
Model 2		1.22	1.13–1.32	1.30	1.20–1.40	1.35	1.25–1.46	1.46	1.35–1.57	<0.001
Women [No. of death]	N = 952	N = 504		N = 486		N = 567		N = 649
Model 1	Reference	1.12	1.01–1.25	1.18	1.05–1.31	1.31	1.18–1.45	1.39	1.26–1.53	<0.001
Model 2		1.12	1.00–1.25	1.15	1.03–1.28	1.28	1.15–1.42	1.37	1.24–1.51	<0.001

Model 1: adjusted for age and sex (only age in stratified analysis). Model 2: adjusted for age, sex, disability, CCI, monthly contribution, insurance type, medical institution type, hypertension, and active ingredients of oral hypoglycemic agents (except sex in stratified analysis).